Imaging Cardiac Phenotype of SARS-Cov-2 (Covid19) Infected Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiomyopathies
- Sponsor
- University Hospital, Toulouse
- Enrollment
- 122
- Locations
- 1
- Primary Endpoint
- Left ventricular function
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The effects of severe acute respiratory syndrome SARS-Cov-2 (Covid-19) on the myocardium and their role in the clinical course of infected patients are still unknown. Epidemiological studies report biological myocardial involvement in 10 to 25% of cases. The objective of this study is to cardiac phenotype using comprehensive cardiac imaging tools of patients infected with Covid 19 in order to explore the functional impact of the infection on the myocardium.
Detailed Description
A large population of Covid 19 infected patients of different ages and severity levels will be explored by transthoracic echocardiography with measurement of myocardial functional parameters such as ejection fraction, longitudinal strain and relaxation parameters and will be compared to an uninfected population paired for age and sex. Patients with biological myocardial involvement will be followed to determine the evolution of their myocardial functional parameters during the course of the infection.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Major patients hospitalized for respiratory criteria for SARS-Cov-2 infection confirmed by RT-PCR
Exclusion Criteria
- •Underage patients. Patients refusing to participate in research. Patients with a history of heart disease.
Outcomes
Primary Outcomes
Left ventricular function
Time Frame: Day 7
Left ventricular function evaluated by global longitudinal strain
Secondary Outcomes
- inflammatory biological parameters(Day 0)