The Clinical Significance of Sentinel Lymph Node Imaging Combined With Imaging Examination in Pelvic and Peritoneal Lymphadenectomy for Endometrial Carcinoma
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Endometrial Carcinoma
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
- Enrollment
- 60
- Primary Endpoint
- the number (s) of pelvic and abdominal lymph node metastasis
- Last Updated
- 5 years ago
Overview
Brief Summary
The aim of this prospective cohort study is to explore the clinical significance of sentinel lymph node imaging combined imaging examination evaluation in pelvic and peritoneal lymphadenectomy for endometrial carcinoma management.
Detailed Description
The clinical data including surgical procedure, the situation of sentinel lymph node imaging and pathological results of patients with endometrial carcinoma treated in our hospitals between April 2019 and April 2021 will be analyzed in this study to clarify the homogeneity of imaging evaluation, sentinel lymph node development evaluation and pathological results.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Females who are diagnosed with endometrial carcinoma;
- •Patients who are willing to receive primary non-reserved fertility function surgery to treat their disease;
- •Patients who are agreed to participated in this prospective cohort study.
Exclusion Criteria
- •Patients who still have the will to have pregnancy;
- •Patients who have other diseases or heavy injuries that will interfere with the results;
- •Simultaneous participation in another clinical study with investigational medicinal product(s) or researcher thinks the subjects are not suitable for this trial.
Outcomes
Primary Outcomes
the number (s) of pelvic and abdominal lymph node metastasis
Time Frame: 1 year during the perioperative period
the specific number of pelvic and abdominal lymph nodes that are invaded by metastatic endometrial carcinoma
the percentage (%) of pelvic and abdominal lymph node metastasis
Time Frame: 1 year during the perioperative period
the specific percentage of pelvic and abdominal lymph nodes that are invaded by metastatic endometrial carcinoma
the coincidence rate (%) of pelvic and abdominal lymph node imaging, sentinel lymph node imaging and pathological diagnosis
Time Frame: 1 year during the perioperative period
by performing chi-square test by SPSS 17.0，we plan to calculate the coincidence rate of three clinical examination
the effect of pelvic lymphadenectomy on the prognosis of endometrial carcinoma patients
Time Frame: 1 year during the perioperative period
by setting up the control group and experimental group and conducting follow-up，we are determined to know whether pelvic lymphadenectomy would influence the prognosis of endometrial carcinoma