The Relationship of PRL and Polycystic Ovary Syndrome (PCOS) in Taiwan's Women

Completed

• Conditions: Polycystic Ovary Syndrome

• Registration Number: NCT01117272
• Lead Sponsor: Taipei Medical University WanFang Hospital

Brief Summary

Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder of reproductive-age women. According to Rotterdam 2003 criteria: at least two of three criteria are met, hyperandrogenism, chronic anovulation, and polycystic ovary. PCOS will cause irregular menstrual cycle, infertility, acne, hirsutism, obesity, or/and metabolic syndrome, diabetes that may increase risk of cardiovascular disease.

Hyperprolactinaemia is also a common problem in reproductive aged women. Both hyperprolactinaemia and PCOS had endocrine disorder and irregular menstrual cycle. Investigators hope to collect clinical data from PCOS and prolactinemia patients followed in Wang Fang hospital for many years in endocrinological and metabolical aspects for comparison. Investigators at the same time would like to understand more about other similarities and differences between these two endocrinological dysfunction for future study.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-05
• Primary Completion: 2010-02
• Study Completion: 2010-04
• Study First Submitted: 2010-05-03
• Study First Submitted QC: 2010-05-04
• Study First Posted: 2010-05-05
• Status Verified: 2013-11
• Last Update Submitted: 2013-11-13
• Last Update Posted: 2013-11-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 474

Inclusion Criteria

• PCOM by ultrasound Diagnosis
• Anovulation, Oligo menses
• Hyperandrogenism

Exclusion Criteria

• Women who had been diagnosed with other etiology that should be excluded in PCOS diagnosis, such as hyperprolactinemia, hypogonadotropic hypogonadism, premature ovarian failure, congenital adrenal hyperplastic, androgen-secreting tumor, Cushing's syndrome, disorders of uterus( such as Asherman's syndrome, Mullerian agenesis), chromosomal anomalies( such as Turner syndrome).
• Women who did not have sufficient clinical or biochemical records.
• Girls who had menarche at <3 years of age and women who were >40 years of age.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
hyperprolactin	Who visited the Reproductive Endocrinology Clinic at Taipei Medical University-Wan Fang Medical Center from April 2004 to June 2007

Trial Locations

Locations (1)

Taipei Medical University WanFang Hospital; 🇨🇳 Taipei, Taiwan