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临床试验/NCT07491250
NCT07491250尚未招募不适用

A Retrospective Study: Complete vs Partial Mesh Removal for Mesh Infection After Hernioplasty - Clinical Outcomes and Pathogen Analysis

Fudan University0 个研究点目标入组 100 人开始时间: 2026年3月18日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
100
主要终点
Hernia Recurrence Rate

研究概览

简要总结

Background: Mesh infection after tension-free inguinal hernia repair (IHR) is rare and challenging. When conservative treatment fails, surgery is often required. This study compared clinical outcomes of complete versus partial mesh removal in affected patients.

Materials and Methods: We retrospectively analyzed patients who underwent surgery for mesh infection after IHR in our hospital between January 2016 and December 2025. Baseline data, perioperative indicators, postoperative complications, and microbiological results were compared between the complete and partial removal groups.

详细描述

We conducted a single-center, retrospective case series analysis. We included patients who developed mesh infection after tension-free IHR and underwent surgical treatment at our center between January 2016 and December 2025. Patients with mesh infection after incisional, parastomal, or umbilical hernia repair were excluded. We also excluded patients who improved with conservative treatment and did not undergo surgery.

We collected the following data: demographic characteristics, comorbidities, laboratory and imaging results, characteristics of the primary hernia surgery, infection characteristics, intraoperative data, and postoperative outcomes. All data were entered into a standardized database. Follow-up was conducted through outpatient visits and telephone interviews. The last follow-up was on October 30, 2025.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who underwent tension-free inguinal hernioplasty with mesh placement.
  • Patients diagnosed with mesh infection requiring surgical re-intervention.
  • Patients who underwent complete or partial mesh removal surgery.
  • Availability of complete medical records and follow-up data.

排除标准

  • Patients with mesh infection managed conservatively (without surgical removal).
  • Patients with missing critical data (e.g., intraoperative findings, pathogen results, or follow-up).
  • Patients with concomitant procedures that could confound outcomes (e.g., simultaneous other hernia repair).
  • Patients lost to follow-up immediately after discharge (no postoperative assessment).

结局指标

主要结局

Hernia Recurrence Rate

时间窗: From date of surgery to December 2025

Presence of clinically or radiologically confirmed recurrent inguinal hernia at the site of previous hernioplasty following mesh removal surgery.

Infection Recurrence Rate

时间窗: From date of surgery to December 2025

Recurrence of surgical site infection at the same location after initial surgical treatment for mesh infection, confirmed by clinical signs (e.g., erythema, purulent drainage, sinus tract formation) and/or positive microbiological culture.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Zhijun Bao

Director

Fudan University

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