NL-OMON54501招募中不适用
In vitro evaluation of the immune-skewing potential of different candidate building blocks for nanoparticle-based allergen immunotherapy for treatment of allergy* - Screening potential allergy vaccine components
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •-Subjects with doctor-diagnosed allergic rhinitis or convincing history of
- •HDM-allergic rhinitis and a positive SPT and/or serum IgE levels for HDM, cat
- •or pollen allergens
- •-Subjects with doctor-diagnosed non-allergic rhinitis or a convincing history
- •of non-allergic rhinitis and a negative SPT and/or no serum IgE levels for HDM,
- •cat or pollen allergens
- •-Subjects with a convincing history of peanut allergy and positive SPT and/or
- •serum IgE levels for peanut allergens
- •-Healthy subjects, defined as not having allergic or non-allergic rhinitis or
- •other inflammatory non-communicable diseases such as rheumatoid arthritis, type
- •2 diabetes, celiac disease, colitis ulcerosa, Chrohn*s disease, and multiple
- •-Aged between 18-65
- •- signed informed consent
排除标准
- •History of AIT (SCIT or SLIT) with any allergen within the past year of the
- •time of blood donation.
- •Ongoing AIT (SCIT or SLIT) with any allergen at the time of blood donation.
- •Vaccination within one week before blood donation.
- •Immunosuppressive or biological medication (e.g. IL-5, anti-IgE therapy)
- •within the last six months prior to blood donation.
- •Severe immune disorders (including auto-immune diseases) and/or diseases
- •requiring immunosuppressive drugs.
- •Active malignancies or any malignant disease during the previous 5 years.
- •Active inflammation or infection at the time of blood donation.
- •Use of systemic steroids within 4 weeks before the blood donation.
- •Treatment with systemic and local β-blockers.
- •Volunteers who are students or employees ofone of the participating research
- •groups or 1st grade relatives or partners of the investigators
研究者
相似试验
尚未招募
不适用
Screening potential allergy vaccine componentsAllergyNL-OMON24623Investigator initiated- Amsterdam university medical centers50
尚未招募
2 期
Evaluation of the Immuno-Stimulatory Potential (Shareera Bala) of an Ayurveda Management Protocol in Cohort of Quarantined Delhi Police under Covid-19 Care Centers- An Exploratory Clinical StudyCTRI/2020/05/025178All India Institute of Ayurveda
进行中（未招募）
2 期
Clinical trial of an Ayurveda InterventioCTRI/2020/06/026103All India Institute of Ayurveda
尚未招募
2 期
Immuno -Modulatory Potential of AyurRaksha Kit and Its Preventive Impact on COVID 19 In Delhi PoliceCTRI/2021/08/035745Ministry of AYUSH
已完成
不适用
In vitro characterization of the immune response of recovered COVID-19 patients and healthy controls to SARS-CoV-2.CoronaCOVID-19SARS-CoV-210047438NL-OMON50131ISA Pharmaceuticals B.V.14