NL-OMON52128已完成不适用
The effects of apple polyphenol supplementation on glucose homeostasis in prediabetic individuals - Glucose homeostasis and apple polyphenols
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
研究概览
简要总结
Trial ended prematurely
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Aged from 40 - 70 years
- •22.5 < BMI < 30 kg/m^2
- •Weight-stable for at least 90 days prior to participation (no change in
- •bodyweight, i.e. < 3kg).
- •HbA1c: 5.7% to 6.4%
- •Fasting blood glucose levels 100 to 125 mg/dl (5.6 to 6.9 mmol/l)
排除标准
- •Subject following an overly imbalanced or restrictive diet as per nutritional
- •Concurrent systemic disease and/or laboratory abnormalities considered by
- •investigators to be detrimental for the participants safety or potentially
- •interfering with the study procedures and/or study outcome
- •Abdominal surgery interfering with gastrointestinal function, upon judgement
- •of the medical doctor, who will decide in-or exclusion based on the surgery
- •Participants who received antibiotics in the 90 days prior to the start of
- •Use of other medication will be reviewed by a medical doctor, who will decide
- •on in- or exclusion based on the drug(s) used
- •Use of laxatives within 14 days prior to the study
- •Using medications for gastric or intestinal complaints
- •Drug use, interfering with any of the outcome parameters of this study; to be
- •decided by the person who is medically responsible for this study
- •Having donated blood in the 3 months prior to the study
- •Administration of antioxidant supplements, investigational drugs or
- •participation in any scientific intervention study, which may interfere with
- •this study (to be decided by the principle investigator), in the 14 days prior
- •to the study
- •History of side effects towards intake of antioxidant supplements
- •Participants who have a gluten or lactose intolerance
- •Use of proton pump inhibitors
研究者
相似试验
终止
不适用
Glucose Homeostasis and Apple PolyphenolsImpaired Glucose ToleranceGlucose Metabolism DisordersPreDiabetesNCT05951270Maastricht University8
已完成
不适用
Polyphenol Supplementation and Morbid Obesity ParametersMorbid ObesityNCT05428540Institut d'Investigació Biomèdica de Bellvitge37
已完成
不适用
Effect of Apple Polyphenols on Vascular Oxidative Stress and Endothelium Function Study (APP trial_2016)Endothelial DysfunctionNCT03053986University of Bologna62
已完成
不适用
Effect of a Polyphenol-rich Food Supplement on Cognitive Function in Healthy Aging AdultsHealthy ElderlyNCT02063646Neurophenols Consortium204
Unknown
2 期
Extension to Study of Effects of Pomegranate Extract on Rising PSA Levels After Primary Therapy for Prostate CancerProstate CancerNCT00732043Roll International Corporation200