Manuka Honey in Second- and Grafted Third-degree Burns

Not Applicable

Recruiting

• Conditions: Second-degree Burn; Third-Degree Burn
• Interventions: Other: wound dressing

• Registration Number: NCT03048188
• Lead Sponsor: University Hospital Schleswig-Holstein

Brief Summary

Treatment strategies of II. degree burn wounds and split-skin grafted III. degree burn wounds aim at reducing infection and improving reepithelialization. The aim of this study is to evaluate time to reepithelialization, pain, microbiology and handling of manuka honey dressings with second-degree burn wounds and split-skin grafted burn wounds.

Detailed Description

In plastic and reconstructive surgery, treatment strategies of second-degree burn wounds and split-skin grafted third-degree burn wounds aim at reducing infection and improving reepithelialization. Although previous studies indicate that burn patients benefit from wound dressings containing manuka honey, only a few studies can be found. Therefore, the aim of this study is to evaluate time to reepithelialization, pain, microbiology and handling of manuka honey dressings with second-degree burn wounds and split-skin grafted burn wounds.

Study Timeline

• Study Start: 2015-07-15
• Study First Submitted: 2017-01-28
• Study First Submitted QC: 2017-02-07
• Study First Posted: 2017-02-09
• Status Verified: 2023-02
• Last Update Submitted: 2023-02-22
• Last Update Posted: 2023-02-24
• Primary Completion: 2023-12
• Study Completion: 2023-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Consent-capable male and female patients (or guardian)
• ≥18 years of age
• ability to asses pain

Exclusion Criteria

• Immunosuppressive Therapy
• Clinical wound infection
• Allergy against honey
• Relationship to someone who is involved in the study design or assessment
• Participation in other clinical trials

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Burn with or without split-skin graft	wound dressing	Second degree burns and third degree burns with split-skin graft that need wound dressings

Primary Outcome Measures

Name	Time	Method
Epithelialization	Up to 1 year	Rate of Epithelialization in percent

Secondary Outcome Measures

Name	Time	Method
Handling	Up to 1 year	Scale (0-4)
Pain	Up to 1 year	Visual analog scale (VAS)
Microbiology	Up to 1 year	Microbiological smear is assessed by gram+, gram- or no bacterium

Trial Locations

Locations (2)

University of Schleswig-Holstein; 🇩🇪 Lübeck, Schleswig-Holstein, Germany

University Hospital Schleswig-Holstein; 🇩🇪 Lübeck, Schleswig-Holstein, Germany