A new ultrasonographic scoring model for stricturing complications in Crohn*s Disease: elastography, contrast-enhanced and small intestinal contrast ultrasonography combined

Withdrawn

• Conditions: Crohn's disease; inflammatory bowel disease; 10018008; 10003816

• Registration Number: NL-OMON45764
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 52

Inclusion Criteria

* Histological confirmed Crohn*s Disease
* Age * 18 year
* Stricturing disease diagnosed by endoscopy and/or radiologic imaging
* Receive medical treatment, endoscopic dilation or surgery

Exclusion Criteria

* * Time between ultrasonography start of medical treatment and baseline ultrasonography and interventional treatment exceeding 8 weeksexceeding two weeks
* Endoscopic balloon dilation prior to baseline ultrasonography
* Pregnancy
* Chronic obstructive lung disease
* Acute coronary heart disease
* Clinically unstable heart disease
* Previous allergic reaction to Sonovue or to its components
* Ongoing gastroenteritis

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Difference of parameters between intervention vs no intervention group:<br /><br>* Speed of velocity of shear-wave (m/s)<br /><br>* Mean transit time of intravascular contrast (second)<br /><br>* Time to peak (second)<br /><br>* Blood volume per tissue (mL/100 mL tissue)<br /><br>* Blood flow (meter per second)</p><br>