Olanzapine versus sodium valproate for the management of aggression in methadone maintenance treatment
Phase 4
- Conditions
- Heroin Withdrawal.Mental and behavioural disorders due to use of opioids
- Registration Number
- IRCT138801241457N5
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 53
Inclusion Criteria
Inclusion Criteria: Methadone Maintenance Treatment, at least one month negative morphine test, age 18 to 55 years old
Exclusion Criteria
Axis I Diagnosis of mental disorders, Diabetes Mellitus or impaired glucose tolerance test, Hyperlipidemia, Hepatic Diseases, abnormal CBC, Positive pregnancy test for women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Aggression. Timepoint: weekly for 12 weeks. Method of measurement: Modified Overt Aggression Scale.
- Secondary Outcome Measures
Name Time Method Relapse rate, and side effects. Timepoint: randomly, 1 to 8 times per month urine test for relapse rate; and weekly evaluation of side effects. Method of measurement: urine test for relapse evaluation; and physical and mental status examination for side effects.