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Clinical Trials/NCT02306226
NCT02306226
Completed
Not Applicable

Symetis ACURATE Neo™ Valve Implantation Using TransFemoral Access: SAVI TF Registry

Symetis SA0 sites1,000 target enrollmentSeptember 2014
ConditionsAortic Stenosis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Aortic Stenosis
Sponsor
Symetis SA
Enrollment
1000
Primary Endpoint
Rate of all-cause mortality
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

Post-market registry aimed at further evaluating the safety and performance of the ACURATE neo™ Aortic Bioprosthesis and ACURATE TF™ Transfemoral Delivery System in patients with severe aortic stenosis treated with the commercialized device

Detailed Description

The SAVI TF is s single arm, multicenter, non-randomized and open registry. The purpose of this registry is to collect and monitor ongoing safety and performance data from commercial use of the ACURATE neo™ Aortic Bioprosthesis and ACURATE TF™ Transfemoral Delivery System. The ACURATE neo™ and its Transfemoral Delivery System are intended for use in minimally invasive, transcatheter aortic valve replacement (TAVR) using transfemoral access in patients presenting with severe aortic valve stenosis. The primary objective is to further evaluate the safety and performance of the ACURATE neo™ Aortic Bioprosthesis and ACURATE TF™ Transfemoral Delivery System in the first 1000 consecutive patients with severe aortic stenosis treated with the newly marketed device. The secondary objective is to evaluate adverse events and device performance of the newly marketed device.

Registry
clinicaltrials.gov
Start Date
September 2014
End Date
April 2017
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Symetis SA
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient is included in the registry if eligible for transcatheter treatment of severe aortic stenosis with the ACURATE neo™ Aortic Bioprosthesis and ACURATE TF™ Transfemoral Delivery System as per the Instructions for Use
  • Patient is willing to participate in the study, provides signed Informed Consent/Data Authorization Form and authorizes the sharing of data in the registry
  • The subject and treating physician agree the subject will return for all required post-procedure follow-up visits

Exclusion Criteria

  • Patients are excluded from the registry if they are not eligible for transcatheter treatment of severe aortic stenosis with the ACURATE neo™ Aortic Bioprosthesis and ACURATE TF™ Transfemoral Delivery System as per the Instructions For Use.

Outcomes

Primary Outcomes

Rate of all-cause mortality

Time Frame: 30 days

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