Maastricht Investigation of Renal function in Absence of- and post- Contrast in patients with estimated glomerular filtration rate LEss than 30mL/min/1.73m2 (MIRACLE)
Withdrawn
- Conditions
- post-contrast acute kidney injurypost-contrast acute increase in serum creatinine10038430
- Registration Number
- NL-OMON54949
- Lead Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 72
Inclusion Criteria
Patients with eGFR <30 mL/min/1.73m2 in absence of dialysis referred for an
elective procedure with intravascular administration of iodinated contrast
material at Maastricht UMC+
Exclusion Criteria
age <18 years; dialysis or pre-dialysis; intravascular contrast administration
within 30 days before the first baseline; emergency or intensive care status;
inability to complete the follow-up.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>In the context of post-contrast acute kidney injury, change in serum creatinine<br /><br>is the gold standard recommended in all (inter)national guidelines on safe use<br /><br>of iodinated contrast material. The primary outcome of the current study is<br /><br>peak changes in serum creatinine within 5 days from a baseline measurement,<br /><br>determined within prespecified periods (see Section J, Table 1). The effect of<br /><br>contrast administration will be expressed as the mean intra-patient difference<br /><br>in peak changes in serum creatinine between 5-day pre- and post-contrast<br /><br>periods. </p><br>
- Secondary Outcome Measures
Name Time Method