Comparison of On-line and Off-line Measurements of Exhaled Nitric Oxide (NO)

• Conditions: Asthma; Primary Ciliary Dyskinesia

• Registration Number: NCT00686309
• Lead Sponsor: Ziv Hospital

Brief Summary

Asthma is a major health problem worldwide. The measurement of fractional exhaled nitric oxide (FENO) has been established as a valuable non invasive and simple tool in the diagnosis of asthma and may also act as a useful surrogate inflammatory marker on which to base treatment decisions in asthma management algorithms. The measurement is useful also in other respiratory diseases. Current methods of measuring FENO include on line measurements by heavy duty expensive analyzers which are not widely and easily available. Off line measurements of breath samples which can be analysed later may be a simple solution. We hypothesize tha toff line measurements of NO will be as reliable and valid as those measured on-line

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2008-05-26
• Study First Submitted QC: 2008-05-28
• Study First Posted: 2008-05-29
• Status Verified: 2009-08
• Last Update Submitted: 2009-08-15
• Last Update Posted: 2009-08-18
• Study Start: 2010-07
• Primary Completion: 2011-07
• Study Completion: 2011-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Volunteer to participate
• Filed a short health questionnaire

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Off line measurement of exhaled NO	Two types of breathing in the same day

Trial Locations

Locations (1)

Pediatric Department, Ziv Medical Center; 🇮🇱 Safed, Israel