Phase II study of Weekly Paclitaxel+Weekly Carboplatin for Platinum/Taxan sensitive recurrent mullerian carcinoma
- Conditions
- Platinum/Taxan sensitive recurrent mullerian carcinoma
- Registration Number
- JPRN-UMIN000003476
- Lead Sponsor
- Japan Kanto Tumor Board(JKTB)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 65
Not provided
1.Progression free interval<6months 2.Prior chemotherapy>2regimen 3.Pleural effusion need to continued drainage. 4.Evidense of severe or uncontrolled cardiac disease. 5.Hystory of myocardial infarction within 6months. 6.Hystory of cirrhosis or active hepatitis. 7.Severe plumonary disease(interstitial pneumonia,pulmonary fibrosis,)8.Gastrointestinal bleeding that requires iteration transfusion. 9.Serius psychological disease. 10.Uncontrolled diabetes. 11.Bowel obstruction. 12.Infection with fever. 13.Active double carcinoma. 14.Symptomatic brain metastasis. 15.Accute inflammatory desease. 16.Sevre peripheral neuropathy. 17.Patients with any history of serious drug reactions 18.History of hyper sensitivity to polyoxyethylene castor oil(ChremophorEL) or contained castor oil(vitamin injection) 19.Pregnant or lactating woman. 20.Any other medical condition that makes the patient unsuitable for inclusion in the study according to the opinion of the investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method