nderstanding how traumatic brain injury-related changes in fluid biomarkers affect quality of life outcomes in veterans

niversity of Birmingham0 个研究点目标入组 90 人开始时间: 2023年12月18日最近更新: 2024年9月2日

适应症

试验速览

2024 Protocol article in https://pubmed.ncbi.nlm.nih.gov/39160095/ (added 20/08/2024)

•Acute TBI group:
•1. Over the age of 18 years
•2. Must have two eyes
•3. Capacity to consent
•4. Willing and able to follow the protocol
•5. Moderate or severe head injury requiring admission to the Queen Elizabeth Hospital within the prior 14 days
•Veterans with TBI group:
•1. Over the age of 18 years
•2. Must have two eyes
•3. Capacity to consent
•4. Willing and able to follow the protocol
•5. Moderate or severe head injury requiring admission to a military hospital facility or service personnel with planned departure from the Armed Forces within 6 months
•Control group:
•1. Over the age of 18 years
•2. Must have two eyes
•3. Capacity to consent
•4. Willing and able to follow the protocol
•5. No prior history of moderate or severe TBI

•Exclusion criteria for all groups:
•1. Patients under 18 years old
•2. Patients registered as sight-impaired or severely sight-impaired
•3. Any known prior pre-existing neuropsychiatric condition: dementia, epilepsy on neuro-epileptic drugs, Parkinson's disease, hereditary neurodegenerative conditions, any known retinal or optic nerve disorder of either eye, pregnancy
•Additional exclusion criteria for the control group only:
•Patients have not suffered a TBI or head injury

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