Traumatic brain injury related changes in military veterans

Not Applicable

• Conditions: Traumatic brain injury; Injury, Occupational Diseases, Poisoning

• Registration Number: ISRCTN13276511
• Lead Sponsor: niversity of Birmingham

Brief Summary

2024 Protocol article in https://pubmed.ncbi.nlm.nih.gov/39160095/ (added 20/08/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2023-12-18
• Last Update Posted: 2 September 2024
• Study Completion: 2025-08-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Acute TBI group:
1. Over the age of 18 years
2. Must have two eyes
3. Capacity to consent
4. Willing and able to follow the protocol
5. Moderate or severe head injury requiring admission to the Queen Elizabeth Hospital within the prior 14 days

Veterans with TBI group:
1. Over the age of 18 years
2. Must have two eyes
3. Capacity to consent
4. Willing and able to follow the protocol
5. Moderate or severe head injury requiring admission to a military hospital facility or service personnel with planned departure from the Armed Forces within 6 months

Control group:
1. Over the age of 18 years
2. Must have two eyes
3. Capacity to consent
4. Willing and able to follow the protocol
5. No prior history of moderate or severe TBI

Exclusion Criteria

Exclusion criteria for all groups:
1. Patients under 18 years old
2. Patients registered as sight-impaired or severely sight-impaired
3. Any known prior pre-existing neuropsychiatric condition: dementia, epilepsy on neuro-epileptic drugs, Parkinson's disease, hereditary neurodegenerative conditions, any known retinal or optic nerve disorder of either eye, pregnancy

Additional exclusion criteria for the control group only:
Patients have not suffered a TBI or head injury

Study & Design

• Study Type: Observational
• Study Design: Not specified