TCI vs. Manuel TIVA in Septorhinoplasty Surgeries

Active, not recruiting

• Conditions: Anesthesia

• Registration Number: NCT06957470
• Lead Sponsor: Bulent Ecevit University

Brief Summary

Septorhinoplasty is a surgical technique that can be used to correct various nasal deformities.Total intravenous anesthesia (TIVA) is a frequently preferred method as an anesthesia technique in septorhinoplasty surgeries.It has been reported that TIVA reduces the incidence of postoperative nausea and vomiting, is more successful in acute postoperative pain control compared to inhalational anesthesia, provides more stable hemodynamics, provides quicker awakening after anesthesia, is more effective in preventing recovery agitation and cough, and is effective in controlled hypotension.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-03-29
• Status Verified: 2025-04
• Study Start: 2025-04-01
• Study First Submitted QC: 2025-05-01
• Last Update Submitted: 2025-05-01
• Study First Posted: 2025-05-04
• Last Update Posted: 2025-05-04
• Primary Completion: 2026-06-01
• Study Completion: 2026-12-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients aged 18-65 years with American Society of Anesthesiology (ASA) physical status I-II who will undergo Septorhinoplasty Surgery under general anesthesia will be included in the study.

Exclusion Criteria

Patients who do not agree to participate in the study Patients under 18 and over 65 Patients with ASA score III and above Clinical diagnosis of neuropsychiatric disorders Those with a history of chronic NSAID, tranquilizer, opioid or sleeping pill use Clinical diagnosis of Serious cardiac diseases Clinical diagnosis of central-autonomic nervous system disease Clinical diagnosis of Coagulopathy Those with soybean oil allergy and a history of allergy to any study drug BMI >30 kg m2, pregnancy breastfeeding patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
postoperative recovery	at postoperative 6 hours and 24 hours	Postoperative recovery will evaluate with quality of recovery-40 questionnaire. quality of recovery-40 scores range from 40 (extremely poor quality of recovery) to 200 (excellent quality of recovery).
agitation during emergence	Postoperative 0 and 15. Minutes at the recovery room	Agitation will evaluate with richmond sedation agitation scale. The richmond sedation agitation scale is a 10-point scale ranging from -5 to +4. Levels -1 to -5 denote 5 levels of sedation, starting with "awakens to voice" and ending with "unarousable." Levels +1 to +4 describe increasing levels of agitation.

Secondary Outcome Measures

Name	Time	Method
surgeon satisfaction	at the end of surgery	5-point Likert Scale
nausea and vomiting	Postoperative 0 hours at recovery room	4-point Likert Scale
postoperative pain	at the end of the surgery	Numeric Rating Scale at the PACU

Trial Locations

Locations (2)

Zonguladk Bulent ecevit University; 🇹🇷 Zonguldak, Kozlu, Turkey

Bulent Ecevit University; 🇹🇷 Zonguldak, Turkey