The Effect of Exposure to Aversive Non-verbal Vocalizations on Pain Tolerance
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 104
- 试验地点
- 2
- 主要终点
- Pain tolerance
研究概览
简要总结
Humans produce non-verbal vocalizations (shouting, growling, screaming), laughter, ...) in various contexts that are likely to perform biological functions.
and important social issues. Yet despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal vocalizations remain little studied and poorly understood including in humans.
In this context, the investigators wish to examine how the perception of vocalizations non-verbal aversive behaviours influence pain tolerance in healthy adults.
详细描述
Humans produce nonverbal vocalisations such as screams, grunts, roars, cries and laughter across a variety of contexts. Yet despite the prominence and apparent importance of these nonverbal sounds in human communication, the investigators still know very little about their influence on human perception and behaviour. That's why, in this study, the investigators will examine specifically the influence of nonverbal vocal perception on pain tolerance.
The remainder of the study will involve up to three trials of a pain tolerance (cold pressor) task, during which the investigators will ask participants to listen to vocalisations (e.g., babies' cries or babbling) while submerging the participant's hand in bath of circulating cold water.
The results of the study will contribute to theoretical understanding of the functions of nonverbal vocal communication in humans, in particular the influence of nonverbal vocal and perception (of babies' cries) on pain tolerance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participant in good health
- •Affiliated or entitled participant in a social security scheme
- •Participant who received informed information about the study and co-signed, with the investigator, a consent to participate in the study
排除标准
- •Chronic pain
- •High blood pressure or poor circulation
- •Cardiac or vascular disease, or a heart condition (including symptoms of Raynaud's syndrome)
- •Allergy or hypersensitivity to cold
- •Pregnancy
- •Recent serious injury
- •Neurological or psychiatric condition known to affect pain tolerance (e.g., peripheral neuropathy, schizophrenia)
- •History of fainting or seizures
- •History of frostbite
结局指标
主要结局
Pain tolerance
时间窗: at inclusion
Delay (in seconds) in removing the hand when testing the Cold Pressor.
次要结局
- Onset of pain(at inclusion)
- Pain intensity(at inclusion)
- Correlation between NOL index and video pupillometry results(at inclusion)