Treatment of Age-related Macular Degeneration Using Retinal Stem and Progenitor Cells

Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus1 site in 1 country20 target enrollmentMarch 1, 2022

ConditionsAge-Related Macular Degeneration

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Age-Related Macular Degeneration
Sponsor: Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Enrollment: 20
Locations: 1
Primary Endpoint: Visual acuity
Status: Enrolling By Invitation
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Treatment of age-related macular degeneration using retinal stem and progenitor cells

Detailed Description

The aim of the project is to develop a biomedical cell product based on retinal pigment epithelium cells for highly effective treatment age-related macular degeneration; to conduct the clinical trials of the biomedical cell product in the treatment of age-related macular degeneration.

Registry

clinicaltrials.gov

Start Date

March 1, 2022

End Date

December 31, 2023

Last Updated

3 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Clinical diagnosis of age-related macular degeneration
•The patient can read, understand, follow the examination procedures and complete, if necessary, the required documentation
•Written informed consent

Exclusion Criteria

•The presence of any malignant tumor within the last 5 years
•Acute or chronic diseases in the stage of decompensation
•Chronic infectious diseases: HIV, viral hepatitis B, C, tuberculosis
•Patients who are pregnant, breastfeeding, or fertile patients who are not using adequate contraceptive methods
•Chronic and protracted mental disorders, all diseases with the presence of the syndrome of dependence on alcohol, drugs and psychoactive substances, any other condition that makes the patient unable to understand the nature, extent and possible consequences of the study or, in the opinion of the researcher, prevents the patient from observing and performing protocol
•Patients are unable or unwilling to give written informed consent and / or follow research procedures
•Any other medical condition that, in the opinion of the investigator, may be associated with an increased risk to the patient or may affect the outcome or evaluation of the study