Treatment of diabetic foot infection with compound Huangbai liquid

Phase 4

Recruiting

• Conditions: Diabetic foot ulcer

• Registration Number: ITMCTR2000004197
• Lead Sponsor: Dongzhimen Hospital, Beijing University of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Patients meeting the diagnostic criteria of diabetic foot;
2. Patients with IDSA grade 2;
3. Culture confirmed the bacteriological basis, and the wound was infected by drug-resistant bacteria;
4. Patients with HbA1c <= 8%;
5. Patients between 18 and 75 years old, male or female;
6. Patients with ABI >= 0.4;
7. Patients with wound area between 1 cm x 1cm and 10 cm x 10cm;
8. Patients who voluntarily participated in the trial and signed the informed consent.

Exclusion Criteria

1. Patients allergic to compound Phellodendron solution and silver ion antibacterial dressing;
2. Patients who used antibiotics in any way within one week before treatment;
3. Serious heart, liver and kidney dysfunction, which seriously affect the safety and treatment of the subjects, should be ruled out by the researchers;
4. Patients with foot ulcer caused by venous, tumor, radiation, simple arterial and other non-diabetic reasons.
5. Patients with serum albumin < 25g / L;
6. Patients with hemoglobin < 90g / L;
7. Patients whose platelets are lower than the lower limit of normal value;
8. Subjects with pregnancy or birth planning, or pregnant or lactating women;
9. Patients with cognitive impairment can not give full informed consent;
10. Patients with allergic constitution or known hypersensitivity to the components of test drug and control drug;
11. Patients who participated in other clinical trials in recent one month;
12. According to the judgment of the researcher, the patient was unable to complete the study or comply with the requirements of the study.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the proportion of resoluting infection;the time of resoluting infection;