NCT02953288UnknownNot Applicable
Differential Diagnosis and Clinical Treatment Strategies of Thyroid Nodules.
Shanghai 10th People's Hospital1 site in 1 country3,000 target enrollmentStarted: October 2016Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 3,000
- Locations
- 1
- Primary Endpoint
- Gene sequencing
Study Overview
Brief Summary
To investigate the genetic mutations of patients with thyroid carcinoma and find molecular targets for therapy.
Detailed Description
In previous studies, we have found highly prevalent TERT promoter mutations in aggressive thyroid cancers. So we plan to perform further research to investigate the genetic mutations of patients with thyroid carcinoma and find molecular targets for therapy.
Study Design
- Study Type
- Observational
- Observational Model
- Case Crossover
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patient with thyroid nodule
Exclusion Criteria
- •Coagulant function abnormality
Outcomes
Primary Outcomes
Gene sequencing
Time Frame: 2 weeks
Secondary Outcomes
No secondary outcomes reported
Investigators
Zhang Manna
Department of Endocrinology
Shanghai 10th People's Hospital
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Molecular Markers in Thyroid CancerThyroid CancerNCT00598364OHSU Knight Cancer Institute847
Terminated
Not Applicable
IDEntification of New Predisposition Genes in Differentiated THYroid CancerDifferentiated Thyroid CancerThyroid Cancer, NonmedullaryNCT05014698Nantes University Hospital34
Completed
Not Applicable
Molecular Analysis for Precision Surgery in Thyroid Cancer TrialPapillary Thyroid CancerNCT06235814University of California, Los Angeles2
Unknown
Not Applicable
Personalized Targeted Therapy in Refractory or Relapsed Cancer in ChildhoodPediatric CancerNCT02242552St. Justine's Hospital30
Recruiting
Not Applicable
Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid TumorsParathyroid Gland AdenomaParathyroid Gland Atypical AdenomaParathyroid Gland CarcinomaPrimary HyperparathyroidismNCT03039439M.D. Anderson Cancer Center310