ISRCTN10431469已完成未知
Cognitive impAiRmEnt Study: Supplementation with the macular carotenoids, vitamin E and fish oil
Waterford Institute of Technology Macular Pigment Research Group0 个研究点目标入组 120 人开始时间: 2015年12月21日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 120
研究概览
简要总结
2020 Results article in https://pubmed.ncbi.nlm.nih.gov/32466168/ Participants with MCI (added 10/06/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34999335/ Cognitively healthy participants (added 10/01/2022)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •MCI participants:
- •1. Males and females aged 65 years and over
- •2. Self or family member reported memory loss
- •3. Functionally independent in activities of daily living (as per BADLS)
- •4. Fulfils criteria for minimal cognitive impairment (as per RBANS)
- •5. Consensus panel agreement on the diagnosis of MCI (where applicable)
- •Non-MCI participants:
- •1. Males and females aged 65 years and over
- •2. Functionally independent in activities of daily living (as per BADLS)
- •3. Confirms absence of any cognitive impairment (as per RBANS)
排除标准
- •1. Active depression (under active review)
- •2. Established diagnosis of early dementia (on cognitive enhancement therapy)
- •3. Current psychiatric illness (under active review of psychotropic medications)
- •4. Stroke disease (clinical stroke or stroke on CT)
- •5. Rapidly progressive or fluctuating symptoms of memory loss
- •6. Already consuming carotenoid supplements (e.g. Macushield) or fish oil supplements (e.g. Souvenaid)
- •7. Already on cholinesterase inhibitors or NMDA receptor antagonists
- •8. Fish allergy
- •9. Acute angle glaucoma
研究者
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