Efficacy and safety assessment of Centella asiatica as a herbal dietary supplement to reduce blood sugar levels in type 2 diabetes patients in Thailand
Phase 2
Recruiting
- Conditions
- Adult patients with type II diabetes mellitusDiabetes Mellitus, Non-Insulin-Dependent
- Registration Number
- TCTR20221219003
- Lead Sponsor
- (in process) the Royal College of Physicians of Thailand
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
1). Age 18-65 years 2). Willing to participate the study 3). Hemoglobin A1C >6.5% or fasting blood sugar >125 mg/d
Exclusion Criteria
1).Pregnancy or breastfeeding 2).Type I diabetes mellitus 3).Hypo- or hyperthyroidism 4).Severe hepatic diseases 5).Severe renal disease 6).Allergic to Centella asiatica 7).Currently treated with injected insulin
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemoglobin A1C 12 weeks percent
- Secondary Outcome Measures
Name Time Method Fasting blood sugar 12 weeks mg/dL,Cytokine (TNF-alpha, IFN-gamma, IL-4, IL-10) 12 weeks pg/mL,Liver function test (AST, ALT) 12 weeks IU/L,Serum creatinine 12 weeks mg/dL,Clinical adverse reactions 12 weeks Clinical adverse reactions,Lipid profile 12 weeks mg/d