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临床试验/CTRI/2025/10/095965
CTRI/2025/10/095965尚未招募2/3 期

A Comparative Clinical Study To Evaluate The Efficacy Of Agasti Modak And Sitopaladi Churna In The Management Of Kaphaj Kasa In Pediatric Age Group

Department Of Kaumarbhritya Shri Narayan Prasad Awasthi Government Ayurved College Raipur CG1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年2月2日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
1.Reduce The Symptoms Of Kasa Vega (Frequency Of Cough)

研究概览

简要总结

Physiologically, kaphaj dosha is more common in balya-awastha and might result in kaphaj kasa and other kaphaj vyadhi. This is among the most prevalent illnesses that impact Pranvaha shrotas and the child’s overall health. An acute respiratory tract infection is linked to upper respiratory disorders. The study includes pediatric patients diagnosed with Kaphaj Kasa, who are randomly divided into two groups

Group A (Trial group) will receive Agasti Modak in oral form, three times daily after meals for 10 days. Dose will be adjusted as per age: 2.5 – 3.5 g (3 – 5 yrs), 3.5 – 5.5 g (6 – 8 yrs), and 4.5 – 6.5 g (9 – 11 yrs).

Group B (Control group) will receive Sitopaladi Churna with Madhu and Ghrita three times daily after meals for 10 days, with age-appropriate dose ranging from 0.2– 0.6 g (3-5 yrs) , 0.4 - 1 g (6-8 ys) and 0.5-1.3 g (9-11yrs)

Follow-up will be done on the 11th day after treatment completion. Assessment will be based on subjective and objective parameters related to the severity and frequency of cough and associated symptoms. Dietary advice (Pathya-Apathya) will be followed during the study.The efficacy of the treatments will be evaluated based on clinical symptoms such as cough frequency, sputum production, and overall improvement in respiratory function. The study seeks to determine which formulation provides better relief and faster recovery, thereby contributing to evidence-based Ayurvedic management of respiratory disorders in children.

Agasti Modak is a classical Ayurvedic formulation mentioned in Bhaisajya Ratnawali It is indicated in Kaphaja Kasa (cough). Agasti modak have seven ingredients they act as bronchodilator, expectorant, and immunomodulatory effects.

Hence, it helps in reducing frequency and severity of cough, relieving airway obstruction, and promoting clearance of respiratory secretions.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
3.00 Year(s) 至 11.00 Year(s)(—)
性别
All

入选标准

  • Patients of either gender from age 3-11 yrs patients have classical symptoms of kasa subject willing to participate in study after consent.

排除标准

  • Patients below 3yr and above 11 yrs Chronic disorders like TB,Pneumonia,RDS,CHD,COPD Pleural effusion Children with any congenital deformity Patients on long term medication as any steroids medicine.

结局指标

主要结局

1.Reduce The Symptoms Of Kasa Vega (Frequency Of Cough)

时间窗: Intervention Of Medicine For 10th Days And Follow Up On 11th Days

2.Reduce Nisthavati Ghanam Kapham (Productive Cough)

时间窗: Intervention Of Medicine For 10th Days And Follow Up On 11th Days

3.Kaphapurna Deha (Heaviness in the body) Reduce

时间窗: Intervention Of Medicine For 10th Days And Follow Up On 11th Days

次要结局

  • Improve the quality of life(At Baseline 10 days of Active intervention)

研究者

发起方
Department Of Kaumarbhritya Shri Narayan Prasad Awasthi Government Ayurved College Raipur CG
申办方类型
Other [Shri Narayan Prasad Awasthi Government Ayurved College Raipur Chhattisgarh 492010]
责任方
Principal Investigator
主要研究者

Dr Yamuna

Shri Narayana Prasad Awasthi Government Ayurved College Raipur

研究点 (1)

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