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An early phase II trial for efficacy and safety of TTA-121 on autism spectrum disorder

Phase 2
Conditions
Autism spectrum disorder
Registration Number
JPRN-UMIN000031412
Lead Sponsor
Hamamatsu University School of Medicine, Department of Psychiatry
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
Male
Target Recruitment
144
Inclusion Criteria

Not provided

Exclusion Criteria

(1) Diagnosis of bipolar disorder or schizophrenia spectrum disorder (2) Primary diagnosis of depressive disorders, obsessive-compulsive and related disorders, anxiety disorders, trauma- and stressor-related disorders, dissociative disorders, somatic symptom and related disorders, or neurodevelopmental disorders other than autism spectrum disorder (3) instability in symptoms of comorbid mental disorders such as depressive disorders or anxiety disorders (4) history of changes in medication or doses of psychotropics within one month before registration (5) current treatment with more than one psychotropics (6) history of hyper-sensitivity to oxytocin; (7) history of seizures or traumatic brain injury with loss of consciousness for longer than 5 minutes (8) history of alcohol-related disorders, substance abuse, or addiction (9) Family history of male breast cancer (10) Subject who has severe complications (11) Known hypersensitivity to some drugs and foods (12) Subject who is not able to consent contraception during study period (13) Pariticipation in another registration clinical trial and administration of investigational drug during 120 days before informed consent (14) Other Subjects whom a lead investigator or the patient's primary physician deems are not appropriate for this study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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