Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes

Not Applicable

Terminated

• Conditions: Gait Disorders, Neurologic

• Registration Number: NCT00139321
• Lead Sponsor: Groupe Hospitalier Pitie-Salpetriere

Brief Summary

Gait disorders and falls are frequent in patients with parkinsonian syndromes. In patients with Parkinson's disease (PD), these signs occurred later during the course of the disease in comparison to patients with other degenerative parkinsonian disorders. The pathophysiology of these symptoms are still not fully understood. Gait initiation challenges the balance control system as the body moves from an upright stable static posture to a continuously unstable gait. The aim of this study is to analyse the gait initiation process in patients with parkinsonian disorders.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-06
• Study First Submitted: 2005-08-30
• Study First Submitted QC: 2005-08-30
• Study First Posted: 2005-08-31
• Primary Completion: 2007-07
• Study Completion: 2007-07
• Status Verified: 2013-01
• Last Update Submitted: 2013-01-07
• Last Update Posted: 2013-01-08

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

• Patients able to walk without assistance
• Patients with Parkinson's disease or other degenerative parkinsonian syndromes (progressive supranuclear palsy [PSP], multiple system atrophy [MSA], corticobasal degeneration [CBD], etc.)

Exclusion Criteria

• Other parkinsonian syndromes
• Dementia
• Neuroleptic treatment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Biomechanical gait initiation parameters

Trial Locations

Locations (1)

Centre d'Investigation Clinique-Hôpital Pitié-Salpetriere; 🇫🇷 Paris, France