Comparison of Postoperative Analgesic Efficacy of Quadratus Lumborum II, Quadratus Lumborum III and Paravertebral Blocks in Elective Laparoscopic Cholecystectomies
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 122
- 试验地点
- 1
- 主要终点
- Total amount of tramadol use
研究概览
简要总结
This trial is a prospective, randomized, single-center, single blinded-analysis trial, the objective of which is compare the postoperative analgesia efficacy of Quadratus lumborum II, Quadratus Lumborum III and Paravertebral blocks in elective laparoscopic cholecystectomy.
详细描述
Laparoscopic approach in cholecystectomy surgery is frequently preferred because of its advantages in systemic complications, morbidity, mortality and hospital stay. Pain is one of the important causes of late discharge after surgery. Laparoscopic cholecystectomy surgery requires a multimodal analgesia approach because of its multiple pain components.Regional analgesia techniques are effective in reducing the side effects such as intraoperative opioid use, postoperative pain and nausea and vomiting. Quadratus lumborum block and paravertebral plane blocks are regional techniques performed for multimodal analgesia.
The aim of this study is to determine an effective analgesia method by comparing the postoperative analgesic effectiveness of Quadratus Lumborum II, Quadratus Lumborum III and Paravertebral blocks in elective laparoscopic cholecystectomy surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 years, American Society of Anesthesiologists physical statusⅠ-II
排除标准
- •local anesthetic allergy
- •Infection at the procedure site
- •Body Mass Index >35 kg/m2
- •Anticoagulant use with bleeding disorder
- •Chronic analgesia and opioid use
- •with mental and psychiatric disorders
研究组 & 干预措施
Quadratus Lumborum Block II
Quadratus Lumborum Block II
干预措施: Quadratus Lumborum Block II (Procedure)
Quadratus Lumborum Block II
Quadratus Lumborum Block II
干预措施: Patient controlled intravenous analgesia (Drug)
Quadratus Lumborum Block III
Quadratus Lumborum Block III
干预措施: Quadratus Lumborum Block III (Procedure)
Quadratus Lumborum Block III
Quadratus Lumborum Block III
干预措施: Patient controlled intravenous analgesia (Drug)
Paravertebral Block
Paravertebral Block
干预措施: Paravertebral Block (Procedure)
Paravertebral Block
Paravertebral Block
干预措施: Patient controlled intravenous analgesia (Drug)
结局指标
主要结局
Total amount of tramadol use
时间窗: within 24 hours after the surgery
The total tramadol use of the patients in 24 hours will be recorded.
次要结局
- postoperative length of hospital stay(within 1 weeks after the surgery)
- Block onset time(30 min after the block)
- intraoperative remifentanil consumption(during operation procedure)
- Visual Analogue Scale values at 1st, 6th, 12th and 24th hours(at 1st, 6th, 12th and 24th hours after the surgery)
- side effects such as nausea, vomiting and shoulder pain(within 24 hours after the surgery)