Comparison of Postoperative Analgesic Efficacy of Quadratus Lumborum II, Quadratus Lumborum III and Paravertebral Blocks in Elective Laparoscopic Cholecystectomies
Overview
- Phase
- Not Applicable
- Intervention
- Quadratus Lumborum Block II
- Conditions
- Postoperative Pain
- Sponsor
- Gaziosmanpasa Research and Education Hospital
- Enrollment
- 122
- Locations
- 1
- Primary Endpoint
- Total amount of tramadol use
- Status
- Completed
- Last Updated
- 9 months ago
Overview
Brief Summary
This trial is a prospective, randomized, single-center, single blinded-analysis trial, the objective of which is compare the postoperative analgesia efficacy of Quadratus lumborum II, Quadratus Lumborum III and Paravertebral blocks in elective laparoscopic cholecystectomy.
Detailed Description
Laparoscopic approach in cholecystectomy surgery is frequently preferred because of its advantages in systemic complications, morbidity, mortality and hospital stay. Pain is one of the important causes of late discharge after surgery. Laparoscopic cholecystectomy surgery requires a multimodal analgesia approach because of its multiple pain components.Regional analgesia techniques are effective in reducing the side effects such as intraoperative opioid use, postoperative pain and nausea and vomiting. Quadratus lumborum block and paravertebral plane blocks are regional techniques performed for multimodal analgesia. The aim of this study is to determine an effective analgesia method by comparing the postoperative analgesic effectiveness of Quadratus Lumborum II, Quadratus Lumborum III and Paravertebral blocks in elective laparoscopic cholecystectomy surgery.
Investigators
Eligibility Criteria
Inclusion Criteria
- •18-65 years, American Society of Anesthesiologists physical statusⅠ-II
Exclusion Criteria
- •local anesthetic allergy
- •Infection at the procedure site
- •Body Mass Index \>35 kg/m2
- •Anticoagulant use with bleeding disorder
- •Chronic analgesia and opioid use
- •with mental and psychiatric disorders
Arms & Interventions
Quadratus Lumborum Block II
Quadratus Lumborum Block II
Intervention: Quadratus Lumborum Block II
Quadratus Lumborum Block II
Quadratus Lumborum Block II
Intervention: Patient controlled intravenous analgesia
Quadratus Lumborum Block III
Quadratus Lumborum Block III
Intervention: Quadratus Lumborum Block III
Quadratus Lumborum Block III
Quadratus Lumborum Block III
Intervention: Patient controlled intravenous analgesia
Paravertebral Block
Paravertebral Block
Intervention: Paravertebral Block
Paravertebral Block
Paravertebral Block
Intervention: Patient controlled intravenous analgesia
Outcomes
Primary Outcomes
Total amount of tramadol use
Time Frame: within 24 hours after the surgery
The total tramadol use of the patients in 24 hours will be recorded.
Secondary Outcomes
- postoperative length of hospital stay(within 1 weeks after the surgery)
- Block onset time(30 min after the block)
- intraoperative remifentanil consumption(during operation procedure)
- Visual Analogue Scale values at 1st, 6th, 12th and 24th hours(at 1st, 6th, 12th and 24th hours after the surgery)
- side effects such as nausea, vomiting and shoulder pain(within 24 hours after the surgery)