Improvement of physical abilities in patients with cystinosis

Phase 1

Completed

• Conditions: Improvement of cardiorespiratory performance and muscle strength in patients with cystinosis; Genetic Diseases

• Registration Number: ISRCTN15626850
• Lead Sponsor: Cystinose Stiftung

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-09-24
• Study Start: 2023-09-21
• Last Update Posted: 3 October 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Confirmed diagnosis of infantile nephropathic cystinosis
2. Prepubertal patients from 6 to 13 years of age or from the age of 18
3. Consent of the patient (18 years and older) or legal representative (for minors)

Exclusion Criteria

1. Patients who are likely to undergo a serious intervention (e.g. kidney transplant, orthopedic surgery) during the duration of the study or for whom there are contraindications for training on Galileo vibration platforms according to the official recommendation
2. Adolescents who have started puberty (boys: testicular volume 3 ml, girls: Tanner stage from B2). Since puberty in these patients starts late, the prepubertal age group was extended to the age of 13 years. The pubertal age group was excluded due to the hormonal changes during this period.

Study & Design

• Study Type: Interventional
• Study Design: Not specified