Effectiveness of Cariprazine vs Amisulpride as add-on treatment options for Negative Symptoms of Schizophrenia- A double blind Pilot RCT - NI

Debibrata Acharya0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年10月16日

试验速览

暂无简介。

•1.18-65 Years old
•2.All patients irrespective of Gender
•3.ICD 10 Diagnosis of Schizophrenia
•4.Clinically Stable defined as total score change =20 % on two sequential ratings (every two weeks for a month) on the positive and negative syndrome scale (PANSS)
•5.Patients providing valid informed consent

•1.Patients with other psychiatric disorders (e.g., schizoaffective disorder, bipolar disorder, severe axis II disorders)
•2.Patients with Treatment resistance (i.e., poor response to =2 antipsychotics of adequate dose and duration during the past 2 years)
•3.Patients with any substance abuse (except nicotine) within 3 months of the study or Patients with substance (with the exception of nicotine) dependence within the last 6 months.
•4.Patients with suicide risk (based on the psychiatric interview or the Columbia-Suicide Severity Rating Scale [C-SSRS])
•5.Patient under treatment of clozapine
•6. Have received electroconvulsive therapy (ECT) in the past 6 months
•7.Active Depressive Symptoms; CDSS score >6
•8.Patients with Intellectual Developmental Disorder (IDD)
•9.Serious medical or neurological illness or seizures
•10.History of neurosurgery or head trauma

发起方

Debibrata Acharya