Research and invention of portable intelligent diagnostic equipment for Liver diseases by Eye Image Analysis based on machine learning in Traditional Chinese medicine
- Conditions
- hepatitis Cirrhosis
- Registration Number
- ITMCTR2000003848
- Lead Sponsor
- Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Aged between 20 and 70 years old (inclusive);
2. It meets the diagnostic criteria of hepatitis B cirrhosis;
3. Liver and gallbladder damp-heat syndrome group: meeting the criteria of disease diagnosis and liver and gallbladder damp-heat syndrome;
4. Liver and kidney yin deficiency syndrome group: meeting the standards of disease and liver and kidney yin deficiency syndrome;
5. Hidden syndrome group: meeting the criteria of disease and hidden syndrome;
6. Normal control group: Healthy volunteers matched with the gender and age of the case group were selected;
7. The person or his guardian agrees to participate in this study and sign the informed consent form.
1. Complicated with conjunctivitis, conjunctival hemorrhage, ocular trauma, surgical eye and other ophthalmic diseases;
2. There are overlapping infections of hepatitis A, C, D and E, fatty liver, or other severe hepatitis;
3. Patients with heart, lung, brain, endocrine, hematopoiesis, nerve and other systemic diseases and allergic to drugs;
4. Patients with malignant tumor and connective tissue disease; Clearly have other important diseases;
5. Pregnant or lactating women and allergic people;
6. Those who have mental disorders can't cooperate;
7. Those who participate in other clinical trials or other situations that researchers think are not suitable for enrollment.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Eye image (eye surface and fundus);
- Secondary Outcome Measures
Name Time Method Magnetic resonance /CT/ elastography /B-ultrasound (liver, gallbladder, pancreas, spleen and kidney), etc;Biochemical examination: liver and kidney function/routine blood test/coagulation/blood lipid;TCM syndrome scale integral (including PRO scale and physical sign scale), tongue picture and pulse picture;