Androgenetic Alopecia in Fabry Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 107
- 试验地点
- 1
- 主要终点
- No and frontal only androgenetic alopecia
研究概览
简要总结
The purpose of this study is to assess whether patients with the classic form of Fabry disease have significantly less androgenic alopecia (male pattern baldness).
详细描述
Objectives: To test the hypothesis that adult males with classic form of Fabry disease have a significantly lower incidence of androgenic alopecia than matched controls.
Study Population: 120 patients aged 20-64 with Fabry disease that have GLA mutations or alpha-galactosidase A activity associated with no residual enzyme activity and non-Fabry male controls of the same age range and the same number of non-Fabry controls.
Design: This is a cross-sectional study comparing the prevalence of androgenic alopecia in two groups of subjects.
Outcome Measures: The levels of the outcome will be no androgenic alopecia and frontal only androgenetic alopecia opposed to vertex only and frontal and vertex androgenetic alopecia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Male patients with Fabry disease age 20-64 years old.
- •Healthy male controls age 20-64 years old
- •GLA gene mutations associated with the classic form of Fabry disease or having alpha-galactosidase A activity that is essentially zero
- •Patients who freely agree to participate in this study and understand the nature, risks and benefits of this study and give their written informed consent.
排除标准
- 未提供
结局指标
主要结局
No and frontal only androgenetic alopecia
时间窗: 1 Year
No and frontal only androgenetic alopecia opposed to vertex only and frontal and vertex androgenetic alopecia.
次要结局
- Vertex only and frontal and vertex androgenetic alopecia.(1 Year)