MedPath

QoLiCOL - Quality of Life in Colon Cancer

Active, not recruiting
Conditions
Colonic Neoplasm
Interventions
Behavioral: There is no intervention, only observation
Registration Number
NCT02530593
Lead Sponsor
Sahlgrenska University Hospital, Sweden
Brief Summary

All patients presenting at participating hospitals during the recruitment period with a newly diagnosed colon cancer, regardless of stage and planned treatment, will be eligible for inclusion. They will answer a questionnaire on health related quality of life, physical symptoms, functional impairments and socioeconomic status at diagnosis and after 12, 36 months. Clinical data including recurrence, survival, surgical treatment, oncologic result (pathology report) and adjuvant treatment will be collected from the Swedish ColoRectal Cancer Registry (SCRCR)

Detailed Description

QoLiCOL is an explorative, prospective, longitudinal, non-interventional, international, multicenter study of health-related quality of life, physical symptoms, functional impairments and socioeconomic burden in colon cancer patients. All patients presenting at participating hospitals during the recruitment period with a newly diagnosed rectal cancer, regardless of stage and planned treatment, will be eligible for inclusion. Patients will be followed for 3 years. They will be asked to answer questionnaires at three different time points during follow-up: at diagnosis and after 12 and 36 months. Clinical data, including recurrence, surgical treatment, oncologic result (pathology report) and adjuvant treatment will be collected from the national quality registry for rectal cancer in Denmark and Sweden. As these registries differ in some areas between the countries, additional data will be collected through short CRF:s.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
1500
Inclusion Criteria
  • Colon cancer newly diagnosed.
  • Planned treatment presented
Exclusion Criteria
  • No Colon cancer diagnosis,
  • below 18 years of age,
  • no informed consent or withdrawn informed consent.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patients with colon cancerThere is no intervention, only observationAll patients presenting with a newly diagnosed colon cancer regardless of tumour stage
Primary Outcome Measures
NameTimeMethod
QoL in colon cancer patients3 years

The primary end-point is to describe QoL, symptoms and functional impairments in an unselected population of colon cancer patients

Secondary Outcome Measures
NameTimeMethod
Generate basic descriptive data of the patient population, such as demography, socioeconomic data, disease stage at diagnosis, type of treatment, recurrence and survival3 years
Compare differences in QoL between patients with different tumour levels3 years
Analyse how clinical factors like oncologic result of operation, morbidity, recurrence and survival influence QoL3 years
Identify areas of improvement in treatment and patient care3 years
Enable initiation interventional studies when appropriate3 years
Detect differences in QoL in patients over time after colon cancer treatment3 years
Evaluate the effect of complications after colon cancer surgery on the patients socioeconomic situation3 years
Evaluate the effect of coping strategies on QoL after initiated treatment3 years
Describe patient expectations at diagnosis of colon cancer3 years
Identify differences in QoL between patients in different groups regarding gender, age and education level3 years
Analyse health economy aspects of QoL and morbidity in the patient population3 years

Trial Locations

Locations (1)

Sahlgrenska University Hospital/Östra

🇸🇪

Göteborg, Sweden

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