EUS-guided radiofrequency ablation for pancreatic neuroendocrine neoplasms

Phase 2

Recruiting

• Conditions: Pancreatic neuroendocrine neoplasms

• Registration Number: JPRN-jRCTs062230014
• Lead Sponsor: Matsumoto Kazuyuki

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-12
• Last Update Posted: 2024-04-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

1. Age more than 18 years old
2. Patient who have been fully informed consent.
3. Pathologically confirmed PNEN with grade by EUS-FNA (WHO 2017 classification)
4. Tumor size 15 mm or less on CE-CT
5. non-functionnal PNEN or insulinom

Exclusion Criteria

1. Allergy for contrast medium
2. Placement of a cardiac pacemaker
3. Within 2 mm of the distance between tumor and main pancreatic duct on radiographic images
4. Suspect of lymph node metastasis or distant metastasis on CE-CT.
5. Less than 50% of PT or less than 1.5 of INR
6. Less than 50,000/ L of PLT
7. Less than 30 mL/min of eGFR
8. Administeration of more than 2 antithrombotic
agents
9. Not less than 2 of performance status
10. Being pregnant or possibly pregnant
11. Less than 5 years of estimated prognosis
12. Patients judged as inappropriate candidate by
the chief medical examiner

Study & Design

• Study Type: Interventional
• Study Design: Not specified