Predisposing Factors Associated With Chemotherapy Toxicity in Elderly Cancer Patients
- Conditions
- Cancer
- Registration Number
- NCT02317757
- Lead Sponsor
- Mahidol University
- Brief Summary
These days, there is higher proportion of elderly cancer patients. Most of them have comorbidities, borderline performance status and nutritional status. The discontinuation of chemotherapy due to unbearable toxicities was not uncommon. Comprehensive geriatric assessment might be beneficial in selection of suitable elderly patients for chemotherapy administration.
- Detailed Description
The patients with the age more than 70 years old who scheduled for chemotherapy were enrolled. Geriatric assessment was performed before starting chemotherapy. The toxicity will be recorded prospectively. Predisposing factors of grade 3 and 4 toxicity will be reported.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
- more than 70 years of age
- plan to receive first cycle of chemotherapy
- histologically or cytologically proved of cancer
Exclusion Criteria
- patients who have concurrent chemoradiotherapy
- patients who received local chemotherapy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method predisposing factors of patients developed grade 3 or 4 chemotherapy toxicity from starting chemotherapy to 1 month after last dose of chemotherapy
- Secondary Outcome Measures
Name Time Method incidence of grade 3 or 4 chemotherapy toxicity in elderly from starting chemotherapy to 1 month after last dose of chemotherapy Factors associated with good quality of life during receiving chemotherapy from starting chemotherapy to 1 month after last dose of chemotherapy
Trial Locations
- Locations (1)
Division of medical oncology, department of medicine Siriraj Hospital
🇹🇭Bangkok, Thailand