Myopia Control Spectacle Lens Cessation Study

Not Applicable

Active, not recruiting

• Conditions: Juvenile Myopia; Myopia; Myopia Progression
• Interventions: Device: Spectacle Lenses

• Registration Number: NCT05893979
• Lead Sponsor: SightGlass Vision, Inc.

Brief Summary

To quantify myopic progression (cycloplegic spherical equivalent refraction - cSER) following the cessation of use of specific spectacle lenses.

To quantify axial length progression following cessation of use of specific spectacle lenses.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-05-30
• Study First Submitted QC: 2023-05-30
• Study First Posted: 2023-06-08
• Study Start: 2023-06-23
• Status Verified: 2024-12
• Last Update Submitted: 2025-05-14
• Last Update Posted: 2025-05-18
• Primary Completion: 2025-12-31
• Study Completion: 2026-07-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Previously a successfully completed participant in the CYPRESS Extension study;
• Agree to wear the assigned spectacles constantly except for sleeping, swimming, or other activities in which spectacle wear would be dangerous or otherwise not possible (minimum of 10 hours per day);
• Willingness to participate in the trial for up to 12 months without contact lens wear;
• The subject's parent(s) or legal guardian(s) must read, understand, and sign the Statement of Informed Consent and receive a fully executed copy of the form.

Exclusion Criteria

• Known allergy to proparacaine, tetracaine, or tropicamide.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control Lens Group	Spectacle Lenses	-
Test Lens Group	Spectacle Lenses	-

Primary Outcome Measures

Name	Time	Method
Cycloplegic Spherical Equivalent Refraction (cSER)	12 months	Change in cSER

Secondary Outcome Measures

Name	Time	Method
Cycloplegic Spherical Equivalent Refraction (cSER)	6 months	Change in cSER
Axial Length (AL)	12 months	Change in AL

Trial Locations

Locations (8)

Golden Optometric Group; 🇺🇸 Whittier, California, United States

Omega Vision Center PA; 🇺🇸 Longwood, Florida, United States

Kannarr Eye Care; 🇺🇸 Pittsburg, Kansas, United States

William J Bogus, OD, FAAO; 🇺🇸 Salt Lake City, Utah, United States

Advanced Eyecare PC; 🇺🇸 Raytown, Missouri, United States

Sacco Eye Group; 🇺🇸 Vestal, New York, United States

Total Eye Care; 🇺🇸 Memphis, Tennessee, United States

Vision Optique; 🇺🇸 Houston, Texas, United States