Effect of a drug on postoperative blood sugar
- Conditions
- Health Condition 1: K829- Disease of gallbladder, unspecifiedHealth Condition 2: K829- Disease of gallbladder, unspecified
- Registration Number
- CTRI/2024/03/063644
- Lead Sponsor
- Dr SN Medical College Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
The patients of aged 18-70 years with Body Mass Index (BMI) ranging from 18.5 to 24.9 kg/m2, American Society of Anesthesiologists (ASA) physical status I and non-diabetic ASA II status posted for elective laparoscopic surgery will be recruited and studied for 72 hours.
Candidates with preexisting diabetes mellitus (FBS more than 126 mg/dl, postprandial blood sugar (PPBS) more than 200 mg/dl, HbA1c more than 6.5),
Chronic steroid therapy (taking steroid more than 10mg, for more than 10 days within last 10 months),
History of allergy to dexamethasone, Pregnancy,
History of peptic ulcer disease,
Malignancy,
Duration of anaesthesia more than 2 hours,
Patients who have history of any vomiting,
Retching, or nausea in the 24 hours preceding the administration of anaesthesia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgeryTimepoint: To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgery
- Secondary Outcome Measures
Name Time Method To compare the incidence of postoperative nausea and vomiting (PONV) <br/ ><br>And Postoperative pain in term of VAS score.Timepoint: Number of nausea and vomiting episodes will be documented 12 hourly and grading will be done accordingly. <br/ ><br>And Postoperative pain will be assessed and documented 12 hourly by using Visual Analogue Scale