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The Effect of Local Injectet GH on the Collagen Synthesis in the Ligamentum Patella

Not Applicable
Completed
Conditions
Growth Hormone
Elderly
Interventions
Registration Number
NCT01158612
Lead Sponsor
University of Aarhus
Brief Summary

Tendon and ligament injuries are a frequent problem among athletes but also in the general population. The healing process is a prolonged process, and complete recovery of tissue strength is nearly never reached. The purpose of this study is to examine the effect of local injection of human Growth Hormone on tendon collagen synthesis.

Detailed Description

Tendon and ligament injuries are a frequent problem among athletes but also in the general population. The healing process is a prolonged process, and complete recovery of tissue strength is nearly never reached. The purpose of this study is to examine the effect of local injection of human Growth Hormone on tendon collagen synthesis.

in order to investigate the collagen synthesis potential and the influence of growth hormone, 12 elderly males age \> 50 year, is enrolled in this study.

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
12
Inclusion Criteria
  • BMI 18.5 - 25.0
Exclusion Criteria
  • earlier knee injury

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
SalineGrowth Hormone-
Growth hormoneGrowth HormoneThe effect of Growth hormone on the collagen synthesis rate
Primary Outcome Measures
NameTimeMethod
• Fraktionele collagen protein synthesis in human patella tendon01122010
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Århus universitetshospital nørrebrogade 44

🇩🇰

Århus C, Denmark

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