Continuous Serratus Anterior Blockade for Sternotomy

Not Applicable

Active, not recruiting

• Conditions: Postoperative Pain; Opioid Use; Quality of Life

• Registration Number: NCT04648774
• Lead Sponsor: Nova Scotia Health Authority

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-11-24
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Inclusion Criteria:<br><br> - Adult (aged >18 years) patients at time of screening<br><br> - Undergoing valvular replacement/repair and/or coronary artery bypass grafting (CABG)<br><br> - via median sternotomy<br><br>Exclusion Criteria:<br><br> - Surgery on an emergency basis (level 1 or 2, <2 hours)<br><br> - An ejection fraction <30%<br><br> - Patient on extracorporeal membrane oxygenator (ECMO),<br><br> - Presence of an intra-aortic balloon pump (IABP)<br><br> - Preoperative vasopressors or inotropes<br><br> - Severe pre-existing liver disease (Child B or C)<br><br> - Severe kidney disease (Glomerular filtration rate (GFR) <30 (mL/min/1·73m²))<br><br> - An allergy to ropivacaine<br><br> - Planned circulatory arrest<br><br> - BMI >35<br><br> - Weight <50 kg<br><br> - Opioid tolerant (oral morphine equivalent >60mg per day for >1 week prior to<br> admission)<br><br> - Unable to provide valid consent to study prior to surgery

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recruitment rate;Adherence rate;Primary outcome measurement rate (quality of recovery 15 index);Combined major block-related adverse event rate

Secondary Outcome Measures

Name	Time	Method
Quality of recovery 15 index (QoR-15);Pain scores;Opioid use