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Clinical Trials/NCT03665272
NCT03665272
Completed
Not Applicable

Evaluation of the Effects of Different Fixation Methods on Wound Healing After Deepithelialized Gingival Graft

TC Erciyes University1 site in 1 country40 target enrollmentJanuary 10, 2018
ConditionsWound Heal

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Wound Heal
Sponsor
TC Erciyes University
Enrollment
40
Locations
1
Primary Endpoint
deepithelialized gingival graft blood perfusion change
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The aim of this study was to compare of the effects of different fixation methods on deepithelialized gingival graft wound healing. Laser doppler flowmetry method was used to determine for blood perfusion changes. 40 patients were devided into two groups randomly and deepithelialized gingival graft procedure was performed and healings were evaluated by laser doppler flowmetry.

Detailed Description

This study evaluates the effects of different fixation methods on the early healing period of deepithelialized gingival grafts placed for non-root coverage gingival augmentation by laser Doppler flowmetry Forty patients were assigned to study groups: 1)test : tissue adhesive or 2) control group: suture. Forty patients completed the study. Blood perfusion in the recipient site was measured by laser doppler flowmetry on the day of surgery and at 3 and 7 days after surgery. Quality of life and pain at recipient sites were also investigated.

Registry
clinicaltrials.gov
Start Date
January 10, 2018
End Date
September 3, 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Zekeriya Tasdemir

Pricipal investigator

TC Erciyes University

Eligibility Criteria

Inclusion Criteria

  • 18 to 65 years of age
  • systemically healthy
  • inadequate amount or absence of keratinized gingiva on the labial side of the lower incisor region
  • no restorations on the lower incisor region
  • no mucogingival surgical history in the lower incisor region
  • no periodontal treatment within the previous year
  • no systemic antibiotics taken for 6 months before the study
  • not pregnant or lactating
  • no-smoking

Exclusion Criteria

  • lower 18 and upper than 65 years of age
  • systemical disease
  • adequate amount of keratinized gingiva on the labial side of the lower incisor region
  • restorations on the lower incisor region
  • mucogingival surgical history in the lower incisor region
  • periodontal treatment within the previous year
  • systemic antibiotics taken for ‡6months before the study
  • pregnancy or lactating
  • smoking history or current smokers

Outcomes

Primary Outcomes

deepithelialized gingival graft blood perfusion change

Time Frame: measurements were performed at the day of surgery, 1, 3 and 7 days.

Blood perfusions (units) were measured by laser doppler flowmetry

Secondary Outcomes

  • Deepithelialized gingival graft recipient bed pain changes(measurements were performed at 1, 3 and 7 days post surgery.)

Study Sites (1)

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