Evaluation of the Effects of Different Fixation Methods on Wound Healing After Deepithelialized Gingival Graft
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- deepithelialized gingival graft blood perfusion change
研究概览
简要总结
The aim of this study was to compare of the effects of different fixation methods on deepithelialized gingival graft wound healing. Laser doppler flowmetry method was used to determine for blood perfusion changes. 40 patients were devided into two groups randomly and deepithelialized gingival graft procedure was performed and healings were evaluated by laser doppler flowmetry.
详细描述
This study evaluates the effects of different fixation methods on the early healing period of deepithelialized gingival grafts placed for non-root coverage gingival augmentation by laser Doppler flowmetry Forty patients were assigned to study groups: 1)test : tissue adhesive or 2) control group: suture. Forty patients completed the study. Blood perfusion in the recipient site was measured by laser doppler flowmetry on the day of surgery and at 3 and 7 days after surgery. Quality of life and pain at recipient sites were also investigated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 to 65 years of age
- •systemically healthy
- •inadequate amount or absence of keratinized gingiva on the labial side of the lower incisor region
- •no restorations on the lower incisor region
- •no mucogingival surgical history in the lower incisor region
- •no periodontal treatment within the previous year
- •no systemic antibiotics taken for 6 months before the study
- •not pregnant or lactating
- •no-smoking
排除标准
- •lower 18 and upper than 65 years of age
- •systemical disease
- •adequate amount of keratinized gingiva on the labial side of the lower incisor region
- •restorations on the lower incisor region
- •mucogingival surgical history in the lower incisor region
- •periodontal treatment within the previous year
- •systemic antibiotics taken for ‡6months before the study
- •pregnancy or lactating
- •smoking history or current smokers
研究组 & 干预措施
fixation by tissue adhesive
In this group, deepithelialized gingival grafts were fixed by tissue adhesive without any suture.
干预措施: deepithelialized gingival graft fixation (Procedure)
fixation by sutures
In this groups, deepithelialized gingival grafts were fixed by 4.0 round vicryl sutures.
干预措施: deepithelialized gingival graft fixation (Procedure)
结局指标
主要结局
deepithelialized gingival graft blood perfusion change
时间窗: measurements were performed at the day of surgery, 1, 3 and 7 days.
Blood perfusions (units) were measured by laser doppler flowmetry
次要结局
- Deepithelialized gingival graft recipient bed pain changes(measurements were performed at 1, 3 and 7 days post surgery.)
研究者
Zekeriya Tasdemir
Pricipal investigator
TC Erciyes University