Glycosylated Hemoglobin and Risk of Perioperative Major Cardiovascular Events in Diabetic Patients Undergoing Coronary Bypass Revascularization (HbA1c)

Completed

• Conditions: Cardiovascular Event; Coronary Artery Bypass Graft; Diabetes Mellitus

• Registration Number: NCT03590223
• Lead Sponsor: University Hospital, Basel, Switzerland

Brief Summary

Glycosylated Hemoglobin (HbA1c) is considered as one of the best markers to assess the glycaemia treatment over a period of 3 to 4 months, and is considered as predictive marker for perioperative mortality and morbidity. The impact of the elevated HbA1c on the risk of perioperative major cardiovascular events in patients undergoing coronary bypass revascularization (by retrospective analysis of perioperative cardiovascular events and preoperative HbA1c) is evaluated.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-12-29
• Study First Submitted: 2018-07-04
• Study First Submitted QC: 2018-07-17
• Study First Posted: 2018-07-18
• Primary Completion: 2018-08-21
• Study Completion: 2018-08-21
• Status Verified: 2021-03
• Last Update Submitted: 2021-03-29
• Last Update Posted: 2021-04-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 589

Inclusion Criteria

• patients with Diabetes mellitus undergoing coronary bypass revascularization since 2012

Exclusion Criteria

• disapproval of use of data for research purposes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
occurence of Major adverse cardiac events	perioperative = in hospital	myocardial infarction, cardiac related death, stroke

Secondary Outcome Measures

Name	Time	Method
occurence of severe renal insufficiency	perioperative = in hospital	application of renal replacement therapy (renal dialysis)
occurence of sternal wound infection	perioperative = in hospital	sternal wound infection
mortality	perioperative = in hospital	death rate perioperative

Trial Locations

Locations (1)

Herzchirurgie University Hospital Basel; 🇨🇭 Basel, Switzerland