Clinical Performance of Two Daily Disposable Toric Soft Contact Lenses

Not Applicable

Completed

Interventions: Device: Verofilcon A toric contact lenses
Device: Etafilcon A toric contact lenses

Brief Summary: The purpose of this study is to compare the clinical performance of PRECISION1™ for Astigmatism (P1fA) contact lenses with 1-DAY ACUVUE MOIST® for ASTIGMATISM (AMfA) contact lenses.

Detailed Description: Subjects will be expected to attend 4 visits and wear study lenses daily for at least 10 hours per day. The total duration of subject participation will be up to 22 days.

Recruitment & Eligibility

Inclusion Criteria

Successful wear of toric soft contact lenses in both eyes for a a minimum of 5 days per week and 10 hours per day during the past 3 months.
Other protocol-defined inclusion criteria may apply.

Exclusion Criteria

Habitual PRECISION1 for Astigmatism or 1-DAY ACUVUE MOIST for ASTIGMATISM contact lens wearers.
Any spherical monovision and multifocal lens wearers.
Routinely sleeping in contact lenses for at least 1 night per week over the last 3 months prior to enrollment.
Other protocol-defined exclusion criteria may apply.

Arm && Interventions

Group	Intervention	Description
P1fA, then AMfA	Verofilcon A toric contact lenses	Verofilcon A toric contact lenses worn first, with etafilcon A toric contact lenses worn second, as randomized. Each study lens type will be worn bilaterally (in both eyes) for 8 -0/+3 days in a daily disposable modality.
P1fA, then AMfA	Etafilcon A toric contact lenses	Verofilcon A toric contact lenses worn first, with etafilcon A toric contact lenses worn second, as randomized. Each study lens type will be worn bilaterally (in both eyes) for 8 -0/+3 days in a daily disposable modality.
AMfA, then P1fA	Verofilcon A toric contact lenses	Etafilcon A toric contact lenses worn first, with verofilcon A toric contact lenses worn second, as randomized. Each study lens type will be worn bilaterally (in both eyes) for 8 -0/+3 days in a daily disposable modality.
AMfA, then P1fA	Etafilcon A toric contact lenses	Etafilcon A toric contact lenses worn first, with verofilcon A toric contact lenses worn second, as randomized. Each study lens type will be worn bilaterally (in both eyes) for 8 -0/+3 days in a daily disposable modality.

Primary Outcome Measures

Name	Time	Method
Least Squares Mean Distance VA (logMAR) With Study Lenses	Day 8 (-0/+3 days), each study lens type	Distance visual acuity (VA) was assessed with study lenses in place. VA was collected for each eye separately using logarithmic of the Minimum Angle of Resolution (logMAR) charts. A logMAR acuity of 0.0 corresponds to 20/20 Snellen acuity (normal visual acuity), with a negative value denoting better than 20/20 visual acuity.

Secondary Outcome Measures

Name	Time	Method

Locations (8): Alcon Investigator 8135
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Los Angeles, California, United States
Alcon Investigator 8062
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Oakland, California, United States
Alcon Investigator 6355
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Orlando, Florida, United States
Alcon Investigator 6614
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Franklin Park, Illinois, United States
Alcon Investigator 3382
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Wyomissing, Pennsylvania, United States
Alcon Investigator 6353
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Memphis, Tennessee, United States
Alcon Investigator 6645
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Shawnee Mission, Kansas, United States
Alcon Investigator 2786
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Memphis, Tennessee, United States