Evaluating the effects of hyaluronic acid mucoadhesive films with two different concentrations on palatal epithelial wound healing and post-operative discomforts after free gingival graft surgery
Not Applicable
Recruiting
- Conditions
- palatal epithelial wound healing and post-operative discomforts after free gingival graft surgery.
- Registration Number
- IRCT20100427003813N12
- Lead Sponsor
- Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 39
Inclusion Criteria
Patients who required free gingival graft;
Presence of sufficient donor tissue dimensions in the palate (length: 10-15 mm, width: 5-8 mm, thickness: 1-1.5 mm).
Exclusion Criteria
Systemic diseases and conditions affecting wound healing (such as uncontrolled diabetes, autoimmune diseases, history of alcoholism);
Presence of attachment loss (greater than 3 mm) in the palatal area of ?premolars and first maxillary molars;
Use of corticosteroids;
Use of antibiotics in the past month;
Pregnancy or breastfeeding;
Smoking.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete epithelialization of the donor site in palate. Timepoint: 3, 7, 14, 21 and 42 days after surgery. Method of measurement: Landry 's healing index.;Color matching, contour and distortion of the donor site in palate. Timepoint: 3, 7, 14, 21 and 42 days after surgery. Method of measurement: Modified Manchester Scar Proforma index.;Postoperative pain. Timepoint: 3, 7, 14 and 21 days after surgery. Method of measurement: Visual analogue scale (VAS).;Patient response to thermal stimulus after surgery. Timepoint: 3, 7, 14 and 21 days after surgery. Method of measurement: Visual analogue scale (VAS).
- Secondary Outcome Measures
Name Time Method