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临床试验/NCT07027085
NCT07027085进行中(未招募)不适用

Investigation of the Effects of Virtual Reality Applications on Sensory Processing, Cognitive Skills, Social Functioning and Disease Symptoms in Individuals Diagnosed With Schizophrenia

Nigde Omer Halisdemir University1 个研究点 分布在 1 个国家目标入组 52 人开始时间: 2025年6月2日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
52
试验地点
1
主要终点
Mini Mental State Examination

研究概览

简要总结

Despite all the positive facts about the use of virtual reality technology in the assessment and treatment of schizophrenia, there are few publications per year. There are few controlled studies covering the effectiveness of virtual reality programs in the training of cognitive and social skills. In future research, more randomized studies with more robust samples are expected, because the results of experimental studies so far encourage this new treatment approach. Therefore, the aim of this study is to examine the effects of virtual reality application on sensory, social and cognitive areas in individuals with schizophrenia.

详细描述

Schizophrenia is a chronic disease that can cause serious disability and negatively affect quality of life and functionality. According to the results of studies conducted to date, it is assumed that schizophrenia is a syndrome rather than a single disease due to its different clinical types, clinical appearance, course and treatment responses that vary from patient to patient. Schizophrenia is one of the diseases that cause the most disability worldwide. According to World Health Organization data, schizophrenia is in the top ten list of diseases that cause disability for individuals aged 15-44. Individuals diagnosed with schizophrenia usually experience difficulties in the areas of Sensory Processing, Cognitive Functions and Social Skills. Sensory processing disorders in individuals with schizophrenia affect the processes of perceiving and interpreting environmental stimuli: Sounds, lights or tactile stimuli that are considered ordinary in daily life may become disturbing or there may be difficulty in combining visual and auditory information in a harmonious way. This situation also negatively affects social interactions. For example, Javitt and Freedman stated that sensory processing disorders in schizophrenia are related to both cognitive and social functioning dimensions of the disease.

Social skills are one of the most frequently affected areas in schizophrenia and various impairments can be observed. Difficulty in social interactions, introversion and communication problems are frequently observed. Difficulty in understanding facial expressions, body language or tone of voice, decreased ability to understand the emotional states of others or avoidance of social interactions and isolation can be observed. Pinkham et al. stated that social cognition is a significant problem in schizophrenia and that this situation has a direct effect on social functioning. Individuals with schizophrenia also experience impairments in their ability to recognize and express emotions. Kohler et al. emphasized that emotional processing disorders in schizophrenia make social relationships even more difficult.

Schizophrenia can lead to significant impairments especially in cognitive areas and this can significantly affect the individual's daily life. For example; difficulty in focusing on a sustained task, deficiencies in the ability to retain and use instant information, or impairments in higher-level cognitive functions such as problem solving, planning, and decision making. A meta-analysis found that individuals with schizophrenia had significant disadvantages compared to healthy individuals in all cognitive areas. One study showed that parietal lobe functions (related to motor planning) may be impaired in individuals with schizophrenia and that this situation has effects on motor control. These problems reduce the quality of life of individuals with schizophrenia and make it difficult for them to reintegrate into society. Innovative approaches such as virtual reality offer promising solutions for rehabilitation in these areas.

Virtual reality (VR) is a technology in which users experience the feeling of being in three-dimensional environments created by computers. This technology abstracts the user from the physical world and includes them in a virtual world through special headsets and sensors.

Virtual reality technology is used in various fields today. In recent years, it has been increasingly used in medicine and psychology. It is especially effective as a rehabilitation and treatment tool in various disease groups. Virtual reality applications have various advantages and limitations. Advantages: Individuals receive therapy in a controlled environment, away from the risks they may encounter in the real world. Virtual reality environments offer more realistic and impressive experiences than traditional therapies. Applications can be customized according to the needs of individuals. Virtual reality devices objectively measure and record the individual's behaviors and reactions. Limitations: The cost of virtual reality equipment and access to technology may be limited. Some individuals may experience side effects such as dizziness or nausea in virtual environments. More research is needed on the long-term effectiveness of some applications. Virtual reality applications in schizophrenia are drawing attention as an innovative approach to improving individuals' cognitive, social and sensory functions. Such applications provide an effective alternative to traditional methods by allowing therapeutic interventions in a safe environment. Virtual reality targets several areas where individuals with schizophrenia have difficulties. These include; Social Skills: Provides safe practice of social interactions by simulating real-life social situations.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Being diagnosed with schizophrenia
  • •Volunteering to participate in the study
  • •Being an adult between the ages of 18-65
  • •Not in an acute or exacerbated phase
  • •Scoring 19 or more on the Mini Mental State Examination

排除标准

  • •Patients who have another psychological or neurological disease other than schizophrenia
  • •Who are unable to give their own consent will not be included in the study.

研究组 & 干预措施

intervention group

Experimental

干预措施: virtual reality (Device)

control group

No Intervention

结局指标

主要结局

Mini Mental State Examination

时间窗: at the beginning (baseline) and end of the intervention (7 weeks)

The Mini Mental State Examination was first published by Folstein et al. (1975). It consists of eleven items grouped under five main headings: orientation, recording memory, attention and calculation, recall, and language, and is evaluated out of a total of 30 points.

Social Functioning Assessment Scale

时间窗: at the beginning (baseline) and end of the intervention (7 weeks)

The Social Functioning Assessment Scale (SAF) will be used for social functioning. This scale, developed in Turkey, assesses social functioning in schizophrenia patients with 19 items and four sub-dimensions. The factors include interpersonal relationships and entertainment with seven items, self-care with seven items, independent living skills with four items, and work life with one item. The score that can be obtained from the scale is between 19 and 57, with a high score indicating a high level of social functioning.

Adolescent/Adult Sensory Profile

时间窗: at the beginning (baseline) and end of the intervention (7 weeks)

The Adolescent/Adult Sensory Profile will be used to examine sensory areas. Adolescent/Adult. Sensory Profile is a scale consisting of 60 items. It evaluates the response of 6 sensory patterns to different sensory stimuli. It is used in adolescents and adults aged 11 and above. The 60 items in the Sensory Profile are divided into four categories, each with 15 items equally divided into four categories, each belonging to a different sensory processing pattern. These are: low registration, sensory seeking, sensory sensitivity, sensory avoidance. Using a five-point Likert scale, participants are asked to rate how often they respond to the sensory event/experience described in each item. Each category results in a score range of 5 to 75. Each age group (11-18, 18-65, and 65 and above) has different norm values. The higher the score, the more characteristics the individual exhibits for sensory processing patterns. For example, the higher the score an individual obtains in the "low-recordin

Schizophrenia Cognitive Assessment Scale

时间窗: at the beginning (baseline) and end of the intervention (7 weeks)

The Schizophrenia Cognitive Assessment Scale (SCAS) will be used for cognitive assessment. The Schizophrenia Cognitive Assessment Scale was developed by Keefe and colleagues in 2005 and consists of 20 items to determine the degree of cognitive impairment and its effects on daily functioning in schizophrenia patients. The items included in the scale were developed to evaluate attention, memory, reasoning and problem solving, working memory, language production and motor skills, which are frequently affected by neurocognitive impairment in schizophrenia patients and closely related to psychosocial functioning. The average application time of the scale is 12 minutes. Each of the 20 items is evaluated on a severity level ranging from 1 to 4, with higher scores indicating a greater degree of impairment. Information is obtained from three separate sources: the patient himself/herself, the patient's relative who provides information, and the interviewer, who is the physician who follows the

次要结局

  • Scale for the Assessment of Positive Symptoms(at the beginning (baseline) and end of the intervention (7 weeks))
  • Scale for the Assessment of Negative Symptoms(at the beginning (baseline) and end of the intervention (7 weeks))

研究者

发起方
Nigde Omer Halisdemir University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Fatıma Zehra Turan

Lecturer

Nigde Omer Halisdemir University

研究点 (1)

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