Effect of subcutaneous nitroglycerin injection on success rate of arterial line placement in critically ill patients with continuous intravenous infusion of vasopressors

Seoul National University Hospital0 个研究点目标入组 136 人开始时间: 待定最近更新: 2021年8月30日

试验速览

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•Among the patients in the surgical intensive care unit who are receiving continuous intravenous infusion of norepinephrine, adult patients (19 years of age or older) who require a arterial catheterization
•– When a new arterial catheterization is needed (ex. malfunction)
•– If there is no severe hemodynamic instability among patients who newly require arterial catheterization

•? Hypersensitivity or contraindication to nitroglycerin (glaucoma, increased intracranial pressure, intracranial hemorrhage, sildenafil or vardenafil)
•? Hypersensitivity or contraindications to lidocaine
•? History of puncture of the radial artery who are planning to attempt arterial catheterization within the last 24 hours
•? Wounds, infections, or hematomas at the site where the arterial line is to be placed
•? Peripheral vascular disease
•? When it is impossible to collect research data on vascular placement due to hemodynamic instability (When norepinephrine requirement is 0.2 µg/kg/min or more)
•? If the patient or surrogates refuses to proceed with the research

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