Myocardial Protection and Clinical Outcome in Patients Undergoing Tetralogy of Fallot Repair : A Randomized Study of Two Different Cardioplegia Technique
Phase 4
Completed
- Conditions
- Myocardial Protection in TOF Repair
- Interventions
- Other: del nido cardioplegiaOther: blood cardioplegia
- Registration Number
- NCT02646254
- Lead Sponsor
- SUNDER LAL NEGI
- Brief Summary
Myocardial protection and clinical outcome in patients Undergoing tetralogy of fallot repair: a randomized study of Two cardioplegic techniques.
- Detailed Description
Del Nido cardioplegia has not been used for myocardial protection and clinical outcome in patients undergoing tetralogy of Fallot repair, so the investigators hypothesized that a del Nido cardioplegia technique may be beneficial in the pediatric patients undergoing tetralogy of fallot repair.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
- Tetralogy of fallot
Exclusion Criteria
- TOF with absent pulmonary valve , TOF with pulmonary atresia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description del nido cardioplegia del nido cardioplegia these patients received del nido cardioplegia blood cardioplegia blood cardioplegia these patients received blood cardioplegia
- Primary Outcome Measures
Name Time Method resumption of spontaneous rhythm after aortic cross clamp off 10 minutes inotropic score First 24 hours Creatine kinase MB level baseline preoperative and postoperative 0, 6, 24, and 72 hours 72hrs
- Secondary Outcome Measures
Name Time Method hospital mortality 30 days duration of mechanical ventilation in hours 48 hours ICU stay 7 days echocardiographic assessment 6 months