MYOCARDIAL PROTECTION AND CLINICAL OUTCOME IN PATIENTS UNDERGOING TETRALOGY OF FALLOT REPAIR: A RANDOMIZED STUDY OF TWO CARDIOPLEGIC TECHNIQUES
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Myocardial Protection in TOF Repair
- Sponsor
- SUNDER LAL NEGI
- Enrollment
- 56
- Primary Endpoint
- resumption of spontaneous rhythm after aortic cross clamp off
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Myocardial protection and clinical outcome in patients Undergoing tetralogy of fallot repair: a randomized study of Two cardioplegic techniques.
Detailed Description
Del Nido cardioplegia has not been used for myocardial protection and clinical outcome in patients undergoing tetralogy of Fallot repair, so the investigators hypothesized that a del Nido cardioplegia technique may be beneficial in the pediatric patients undergoing tetralogy of fallot repair.
Investigators
SUNDER LAL NEGI
Fellow, Cardiac anesthesia.
Post Graduate Institute of Medical Education and Research, Chandigarh
Eligibility Criteria
Inclusion Criteria
- •Tetralogy of fallot
Exclusion Criteria
- •TOF with absent pulmonary valve , TOF with pulmonary atresia
Outcomes
Primary Outcomes
resumption of spontaneous rhythm after aortic cross clamp off
Time Frame: 10 minutes
inotropic score
Time Frame: First 24 hours
Creatine kinase MB level baseline preoperative and postoperative 0, 6, 24, and 72 hours
Time Frame: 72hrs
Secondary Outcomes
- hospital mortality(30 days)
- duration of mechanical ventilation in hours(48 hours)
- ICU stay(7 days)
- echocardiographic assessment(6 months)