MYOCARDIAL PROTECTION AND CLINICAL OUTCOME IN PATIENTS UNDERGOING TETRALOGY OF FALLOT REPAIR: A RANDOMIZED STUDY OF TWO CARDIOPLEGIC TECHNIQUES
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 56
- 主要终点
- resumption of spontaneous rhythm after aortic cross clamp off
研究概览
简要总结
Myocardial protection and clinical outcome in patients Undergoing tetralogy of fallot repair: a randomized study of Two cardioplegic techniques.
详细描述
Del Nido cardioplegia has not been used for myocardial protection and clinical outcome in patients undergoing tetralogy of Fallot repair, so the investigators hypothesized that a del Nido cardioplegia technique may be beneficial in the pediatric patients undergoing tetralogy of fallot repair.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 1 Year 至 50 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Tetralogy of fallot
排除标准
- •TOF with absent pulmonary valve , TOF with pulmonary atresia
结局指标
主要结局
resumption of spontaneous rhythm after aortic cross clamp off
时间窗: 10 minutes
inotropic score
时间窗: First 24 hours
Creatine kinase MB level baseline preoperative and postoperative 0, 6, 24, and 72 hours
时间窗: 72hrs
次要结局
- hospital mortality(30 days)
- duration of mechanical ventilation in hours(48 hours)
- ICU stay(7 days)
- echocardiographic assessment(6 months)
研究者
SUNDER LAL NEGI
Fellow, Cardiac anesthesia.
Post Graduate Institute of Medical Education and Research, Chandigarh