NCT02852850Unknown不适用
In Vivo Molecular Imaging With Infliximab Antibody With FITC Predicts Therapeutic Response in Ulcerative Colitis
Shandong University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2016年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- The number of specific fluorescence signal of mTNF+ cells in patients with UC
研究概览
简要总结
Molecular imaging with infliximab antibody with FITC has the potential to predict therapeutic responses to infliximab antibody and can be used for personalized medicine in ulcerative colitis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with active ulcerative colitis will receive infliximab antibody therapy.
排除标准
- •Patients with impaired blood clotting.
- •Patients with short bowel syndrome.
- •Patients during the pregnancy and lactation period.
- •Patients received enema therapy within 1 month before inclusion in the study, or had anti-TNF therapy within the last 12 months.
- •Patients participated in another clinical trial or administrated other investigational drugs within 4 months prior to the screening visit.
- •Patients with moderate to severe heart failure, active tuberculosis or acute infections.
结局指标
主要结局
The number of specific fluorescence signal of mTNF+ cells in patients with UC
时间窗: 30 months
次要结局
未报告次要终点
研究者
Yanqing Li
Vice president of Qilu Hospital
Shandong University
研究点 (1)
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