Emotions Analysis in Patients With Chronic Phase of Stroke Basal Ganglia

Not Applicable

Terminated

• Conditions: Stroke Basal Ganglia

• Registration Number: NCT02884882
• Lead Sponsor: University Hospital, Brest

Brief Summary

Compare the emotional experience of patients with focal lesions of the basal ganglia by ischemic or hemorrhagic damage and healthy participants. These anomalies will be highlighted by neuropsychological and electrophysiological assessments.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-12
• Study First Submitted: 2016-08-26
• Study First Submitted QC: 2016-08-26
• Study First Posted: 2016-08-31
• Primary Completion: 2018-04
• Study Completion: 2018-04
• Status Verified: 2018-11
• Last Update Submitted: 2018-11-27
• Last Update Posted: 2018-11-28

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 149

Inclusion Criteria

• For cases :

  • right-handed patient
  • ischemic or hemorrhagic stroke older than 3 months with single lesion preferably less than 20 mm in diameter affecting the basal ganglia and sparing cortex
  • Rankin score estimated prior stroke must be equal to 0 and after stroke <3 (at inclusion).

• For participants control : right-handed patient

Exclusion Criteria

• For cases : severe aphasia - Prosopagnosia apperceptive - cerebral neurological pathology associated history, especially dementia - History of depression and psychiatric disorders treated - another stroke vascular territory than that for which the patient is included - diffuse lesions of the white matter Fazekas a score of> 2 (periventricular or subcortical) - Contraindications to MRI
• For participants control : No history neurosurgical - No history of head trauma with loss of consciousness - not known neurological disease - not known psychiatric illness - No psychotropic treatment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The emotional experience	Baseline	The emotional response will be compared between patients with focal lesion cores by ischemic or hemorrhagic reached that of healthy participants.; Score (from 1 to 10) rated the felt for each target emotions for the following 6 dimensions: joy, sadness, fear, disgust, anger, no emotion, after the presentation of short sequences of standardized films. Six films are presented, each after a relaxation period after which the basal score is measured.

Secondary Outcome Measures

Name	Time	Method
The recognition of facial expressions	Baseline	The facial expression recognition will be compared between patients with focal lesion cores by ischemic or hemorrhagic reached that of healthy participants.; Percentage of recognition of facial emotions expression for each of the following 7 sizes: joy, sadness, fear, surprise, disgust, anger, no emotion; 8 frames per dimensions are presented on a total of 56 facial expressions (Ekman \& Friesen, and Karolinska series).

Trial Locations

Locations (1)

Centre Hospitalier Régional Universitaire de Brest; 🇫🇷 Brest, France