ISRCTN47102251已完成未知
Antibiotic-lock technique with Taurolidine for prevention of central venous catheter infection in neutropenic patients: a randomized, double-blind, placebo-controlled study
The Carlos III Health Institute (Instituto de Salud Carlos III)0 个研究点目标入组 150 人开始时间: 2015年10月21日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 150
研究概览
简要总结
2018 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/29720244 2020 results in https://pubmed.ncbi.nlm.nih.gov/31712211/ (added 25/02/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Adult patients aged > 18 years
- •2. Hospitalized with leukemia, lymphoma or stem cell transplantation
- •3. Carry a central venous catheter
- •4. Likely to develop neutropenia (<500 neutrophils per ul) lasting more than one week
排除标准
- •1. Patients with a (not flexible) semi-rigid central venous catheter
- •2. Patients who have been found to have a positive culture of the hubs or the insertion site of the catheter, previously to randomization
- •3. Patients in whom the central venous catheter is used for parenteral nutrition or medication that needs continuous infusion
- •4. Patients receiving systemic antibiotic treatment = 48 hours
- •5. Patients who have an active infection at the baseline statement
研究者
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